- Application of Bethesda System for Reporting Thyroid Aspiration Cytology.
-
Kyungji Lee, Chan Kwon Jung, Kyo Young Lee, Ja Seong Bae, Dong Jun Lim, So Lyung Jung
-
Korean J Pathol. 2010;44(5):521-527.
-
DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.5.521
-
-
4,613
View
-
61
Download
-
20
Crossref
-
 Abstract
 PDF
- BACKGROUND
The Bethesda classification system for reporting on thyroid fine-needle aspiration (FNA) cytology was recently proposed by the National Cancer Institute, USA. We aimed to report our experience with applying this system for thyroid FNA, with a focus on comparing it with the four categorical system.
METHODS
We retrospectively reviewed the 4,966 thyroid FNAs that were performed at the Seoul St. Mary's Hospital between October 2008 and September 2009. All the FNAs were classified according to the Bethesda system and the four tier system.
RESULTS
The cytologic diagnoses of the Bethesda system included 10.0% unsatisfactory, 67.7% benign, 3.1% atypia of undetermined significance, 0.6% follicular neoplasm, 0.5% follicular neoplasm, Hurthle cell type, 5.1% suspicious for malignancy and 13.0% malignancy. Using four tier system, 10.1%, 67.6%, 9.3%, and 13% were diagnosed as unsatisfactory, negative for malignancy, atypical cells and malignancy, respectively. Of the 4,966 nodules, 905 were histologically confirmed. The specificity of the Bethesda system and the four tier system for diagnosing malignancy was 99.6% and 82.6%, respectively.
CONCLUSIONS
The Bethesda system can classify indeterminate thyroid nodules into more detailed categories and provide clinicians with useful information for management.
-
Citations
Citations to this article as recorded by  - The Bethesda System for Reporting Thyroid Cytopathology: Validating at Tribhuvan University Teaching Hospital
Kunjan Acharya, Shreya Shrivastav, Prashant Triipathi, Bigyan Raj Gyawali, Bijaya Kharel, Dharma Kanta Baskota, Pallavi Sinha
International Archives of Otorhinolaryngology.2022; 26(01): e097. CrossRef - Ultrasound-guided fine needle aspiration cytology and ultrasound examination of thyroid nodules in the UAE: A comparison
Suhail Al-Salam, Charu Sharma, Maysam T. Abu Sa’a, Bachar Afandi, Khaled M. Aldahmani, Alia Al Dhaheri, Hayat Yahya, Duha Al Naqbi, Esraa Al Zuraiqi, Baraa Kamal Mohamed, Shamsa Ahmed Almansoori, Meera Al Zaabi, Aysha Al Derei, Amal Al Shamsi, Juma Al Kaa
PLOS ONE.2021; 16(4): e0247807. CrossRef - Subclassification of the Bethesda Category III (AUS/FLUS): A study of thyroid FNA cytology based on ThinPrep slides from the National Cancer Center in China
Huan Zhao, HuiQin Guo, LinLin Zhao, Jian Cao, Yue Sun, Cong Wang, ZhiHui Zhang
Cancer Cytopathology.2021; 129(8): 642. CrossRef - McGill Thyroid Nodule Score in Differentiating Thyroid Nodules in Total Thyroidectomy Cases of Indeterminate Nodules
Hadi A Al-Hakami, Reem Al-Mohammadi, Rami Al-Mutairi, Haya Al-Subaie, Mohammed A Al Garni
Indian Journal of Surgical Oncology.2020; 11(2): 268. CrossRef - Fine-needle aspiration cytology of nodular thyroid lesions: A 1-year experience of the thyroid cytopathology in a large regional and a University Hospital, with histological correlation
Kaumudi Konkay, Radhika Kottu, Mutheeswaraiah Yootla, Narendra Hulikal
Thyroid Research and Practice.2019; 16(2): 60. CrossRef - Reproducibility of atypia of undetermined significance/follicular lesion of undetermined significance category using the bethesda system for reporting thyroid cytology when reviewing slides from different institutions: A study of interobserver variability
Vijayalakshmi Padmanabhan, Carrie B Marshall, Guliz Akdas Barkan, Mohiedean Ghofrani, Alice Laser, Idris Tolgay Ocal, Charles David Sturgis, Rhona Souers, Daniel F.I Kurtycz
Diagnostic Cytopathology.2017; 45(5): 399. CrossRef - The Use of the Bethesda System for Reporting Thyroid Cytopathology in Korea: A Nationwide Multicenter Survey by the Korean Society of Endocrine Pathologists
Mimi Kim, Hyo Jin Park, Hye Sook Min, Hyeong Ju Kwon, Chan Kwon Jung, Seoung Wan Chae, Hyun Ju Yoo, Yoo Duk Choi, Mi Ja Lee, Jeong Ja Kwak, Dong Eun Song, Dong Hoon Kim, Hye Kyung Lee, Ji Yeon Kim, Sook Hee Hong, Jang Sihn Sohn, Hyun Seung Lee, So Yeon Pa
Journal of Pathology and Translational Medicine.2017; 51(4): 410. CrossRef - Thyroid FNA cytology in Asian practice—Active surveillance for indeterminate thyroid nodules reduces overtreatment of thyroid carcinomas
K. Kakudo, M. Higuchi, M. Hirokawa, S. Satoh, C. K. Jung, A. Bychkov
Cytopathology.2017; 28(6): 455. CrossRef - Bethesda System for Reporting Thyroid Cytopathology: A three-year study at a tertiary care referral center in Saudi Arabia
Mohamed Abdulaziz Al Dawish, Asirvatham Alwin Robert, Aljuboury Muna, Alkharashi Eyad, Abdullah Al Ghamdi, Khalid Al Hajeri, Mohammed A Thabet, Rim Braham
World Journal of Clinical Oncology.2017; 8(2): 151. CrossRef - Thyroid Fine-Needle Aspiration Cytology Practice in Korea
Yoon Jin Cha, Ju Yeon Pyo, SoonWon Hong, Jae Yeon Seok, Kyung-Ju Kim, Jee-Young Han, Jeong Mo Bae, Hyeong Ju Kwon, Yeejeong Kim, Kyueng-Whan Min, Soonae Oak, Sunhee Chang
Journal of Pathology and Translational Medicine.2017; 51(6): 521. CrossRef - Malignancy Risk for Fine-Needle Aspiration of Thyroid Nodules according to the Bethesda System for Reporting Thyroid Cytopathology, at King Abdul-Aziz, National Guard Hospital
Omimah Abdullah
Journal of Otolaryngology-ENT Research.2017;[Epub] CrossRef - The Bethesda System for Reporting Thyroid Fine-Needle Aspiration Cytology: A Kuwaiti Experience - A Cytohistopathological Study of 374 Cases
Kusum Kapila, Laila Qadan, Rola H. Ali, Mohammed Jaragh, Sara S. George, Bahiya E. Haji
Acta Cytologica.2015; 59(2): 133. CrossRef - Review of the Bethesda System for Reporting Thyroid Cytopathology: A Local Study in Bohol Island, Philippines
Annette L. Salillas, Faye Candice S. Sun, Emelisa G. Almocera
Acta Cytologica.2015; 59(1): 77. CrossRef - The role of core needle biopsy in the preoperative diagnosis of follicular neoplasm of the thyroid
Hye Sook Min, Ji‐Hoon Kim, Inseon Ryoo, So Lyung Jung, Chan Kwon Jung
APMIS.2014; 122(10): 993. CrossRef - Incidence and Malignancy Rates of Diagnoses in the Bethesda System for Reporting Thyroid Aspiration Cytology: An Institutional Experience
Ji Hye Park, Sun Och Yoon, Eun Ju Son, Hye Min Kim, Ji Hae Nahm, SoonWon Hong
Korean Journal of Pathology.2014; 48(2): 133. CrossRef - Thyroid “Atypia of undetermined significance” with nuclear atypia has high rates of malignancy and BRAF mutation
Hyo Jin Park, Jae Hoon Moon, Cha Kyong Yom, Kyu Hyung Kim, June Young Choi, Sang Il Choi, Soon‐Hyun Ahn, Woo‐Jin Jeong, Won Woo Lee, So Yeon Park
Cancer Cytopathology.2014; 122(7): 512. CrossRef - Molecular Genotyping of Follicular Variant of Papillary Thyroid Carcinoma Correlates with Diagnostic Category of Fine-Needle Aspiration Cytology: Values of RAS Mutation Testing
Sang Ryung Lee, Chan Kwon Jung, Tae Eun Kim, Ja Seong Bae, So Lyung Jung, Yeong Jin Choi, Chang Suk Kang
Thyroid.2013; 23(11): 1416. CrossRef - Fine Needle Aspiration Cytology of Thyroid Follicular Neoplasm: Cytohistologic Correlation and Accuracy
Changyoung Yoo, Hyun Joo Choi, Soyoung Im, Ji Han Jung, Kiouk Min, Chang Suk Kang, Young-Jin Suh
Korean Journal of Pathology.2013; 47(1): 61. CrossRef - Diagnostic Dilemma of a Follicular Lesions/Neoplasm in Thyroid Fine Needle Aspiration Cytology
Chan Kwon Jung
Journal of Korean Thyroid Association.2012; 5(2): 104. CrossRef - Review of atypical cytology of thyroid nodule according to the Bethesda system and its beneficial effect in the surgical treatment of papillary carcinoma
Yoo Seung Chung, Changyoung Yoo, Ji Han Jung, Hyun Joo Choi, Young-Jin Suh
Journal of the Korean Surgical Society.2011; 81(2): 75. CrossRef
|
E-submission
